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Today is the six year anniversary of completing our circumnavigation (May 1, 2009).

Choice of Antihypertensive Combination Therapy Based on Daily Salt Intake.

Data are lacking on how treatment of lower threshold hyperglycemia impacts prognosis of future diabetes for the mother and future obesity, diabetes risk, or other metabolic consequences for the offspring.

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In the presence of proliferative diabetic retinopathy (PDR) or severe nonproliferative diabetic retinopathy (NPDR), vigorous aerobic or resistance exercise may be contraindicated because of the risk of triggering vitreous hemorrhage or retinal detachment ().

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THE IMPORTANCE OF RENIN-ANGIOTENSIN BLOCKADE IN PATIENTS WITH CARDIO-RENAL DISEASE.

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Based on these studies, the most common side effect was dizziness, occurring in up to 3 percent of people.

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Managing Chronic Kidney Disease in Type 2 Diabetes in Family Practice.

When prescribing SMBG, ensure that patients receive ongoing instruction and regular evaluation of SMBG technique and SMBG results, as well as their ability to use SMBG data to adjust therapy.

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Compared to baseline, DBP and SBP were reduced by approximately 12 and 15 mm Hg, respectively, in subjects treated with olmesartan medoxomil at the recommended starting dosage of 20 mg once daily.

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Olmesartan is a specific angiotensin II type 1 (AT1) receptor antagonist, which blocks the blood pressure increasing effects of angiotensin II via the renin-angiotensin-aldosterone system (RAAS).

Death from cardiovascular causes was defined as a death attributed to sudden death from cardiac causes, myocardial infarction, stroke, coronary intervention, congestive heart failure, or other cardiovascular causes.

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See separate drug interaction monographs for agents listed as exceptions.

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Call for the use of a common equation for glomerular filtration rate estimation in East and South-East Asia.

To achieve glycemic targets associated with improved hospital outcomes, hospitals will need multidisciplinary support to develop insulin management protocols that effectively and safely enable achievement of glycemic targets ().

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If you have diabetes, do not use amlodipine, hydrochlorothiazide, and olmesartan together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

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Changes in RAS activity and activation of the VDR seem to be inversely related, making it possible to speculate that both systems could have a feedback relationship.

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At the end of the study, 24-hour ambulatory blood-pressure monitoring was performed in 568 patients (270 in the olmesartan group and 298 in the placebo group).

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In recent years, hypertension patients have tended to use multiple hypotensive drugs with different action mechanisms in combination in order to achieve reliable blood pressure control.

Patient-directed titration for achieving glycaemic goals using a once-daily basal insulin analogue: an assessment of two different fasting plasma glucose targets - the TITRATE study.

The Prevention of Progression of Arterial Disease and Diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.

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Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

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Advise patients that lightheadedness can occur, especially during the first days of therapy, and to report this symptom to a healthcare provider.

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This generally includes most men over age 50 years and women over age 60 years who also have one or more of the following major risk factors: 1) smoking, 2) hypertension, 3) dyslipidemia, 4) family history of premature CVD, and 5) albuminuria ().

Similarly, simultaneous therapy with calcium-channel antagonists did not detract from the beneficial effects of losartan, despite the recent controversy regarding the role of calcium-channel antagonists in the protection of the kidneys and the heart.

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DPP are cost-effective (), and actual cost data from the DPP and DPPOS confirm that lifestyle interventions are highly cost-effective ().

Safety standards should be established for blood glucose monitoring prohibiting sharing of finger-stick lancing devices, lancets, needles, and meters to reduce the risk of transmission of blood-borne diseases.

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Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the Look AHEAD trial.

Adjust the lithium dose as needed.

The US labeling makes no recommendation regarding continuation or discontinuation of valsartan for breast-feeding mothers.

The trough blood pressure declined progressively during the course of the study.

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Wienen W, Entzeroth M, van Meel JCA, et al: A review on telmisartan: a novel, long-acting angiotensin II-receptor antagonist.

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Beta-blockers should be started with very low doses and increased gradually to a target maintenance dose.

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Our study establishes that losartan, along with conventional antihypertensive treatment as needed, confers strong renal protection in patients with type 2 diabetes and nephropathy.

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