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I work as an international journalist and I travel a lot to countries with exotic nature. Every time when I am about to direct my steps to regions with malaria I take a course of Chloroquine. It helps me keep away from the disease and come back healthy. These medications can not be taken on a regular basis because of being very strong. So don't forget to consult with your doctor if you plan a trip to contaminated area. Malaria is a horrible disease and if you can prevent it don't hesitate. People talk about awful side effects after taking medications from malaria, but what I think is that vomiting and sweating is better than death anyway. The only side effect I experienced after starting on Chloroquine was mild fatigue. It soon disappeared though. So, think twice and then act!
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De combinatie van chloroquine met kan effectiever zijn bij de behandeling van chloroquine-resistente dan met chloroquine alleen.
If the disease appears to be severe, especially in the lungs, eyes, heart, nervous system, spleen, or kidneys, the doctor may prescribe corticosteroid.
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In countries where the disease is seen a lot, it's not uncommon for doctors to treat people for malaria who have fever of no obvious cause without getting laboratory confirmation.
NO, you do not need to have regular blood tests while taking Chloroquine.
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These tests appeared to be highly specific (100%), since none were positive with sera from 15 Thai control patients, 6 serum samples containing cryptococcal antigen, or 6 urine specimens positive for Histoplasma polysaccharide antigens.
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First, as chloroquine is deployed in an afflicted country, the initial ultra-rare two required mutations eventually appear together in one cell (the deleterious-by-itself K76T plus a second mutation that confers transporting activity) and are selected to survive in the presence of chloroquine.
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A) Vero E6 cells were cultured for 20 h in the absence (control) or presence of chloroquine (10 μM) or NH 4Cl (20 mM).
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The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme that is associated with the resulting phagolysosome gen- erates a mixture of ROSs, superoxide anions that then dismutate to body H2O2 and interact with the peroxide to frame hydroxyl radicals.
An exploratory analysis of subgroups defined according to known prognostic factors demonstrated a survival benefit in nearly all subgroups.
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An infectious disease characterized by cycles of chills, fever, and sweating, caused by a protozoan of the genus Plasmodium in red blood cells, which is transmitted to humans by the bite of an infected female anopheles mosquito.
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Antihistamines are also given to provide relief for itchiness but are not as effective as corticosteroids.
Chloroquine bindt ook aan het (FP) zelf, waarbij een zeer giftig complex ontstaat (FP-chloroquine) dat de membraanfuncties van de cel verstoort.
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